SELECT 
  combination 
FROM 
  cscart_product_options_inventory 
WHERE 
  product_id = 10961 
  AND amount > 0 
  AND combination != ''

Query time 0.00039

Explain
id select_type table type possible_keys key key_len ref rows Extra
1 SIMPLE cscart_product_options_inventory range pc pc 770 46 Using index condition; Using where